Samurai Warriors Edit

Mitsuhide is a venerable general who desires to see a peaceful land. He is Ranmaru's mentor and a vassal of the Saitō family. Losing faith in their current master, both he and his pupil desire to join Nobunaga at Inabayama Castle. Proving their worth through combat, they join the Oda ranks and enter the front lines at Ise-Nagashima. Unprepared for the sheer brutality towards the Honganji Rioters, however, Mitsuhide is devastated by Nobunaga's strategies. Several years later, he betrays Nobunaga at Honnōji in the belief that his actions can rectify the sorrow his lord causes. Knowing that his pupil will stay true to Nobunaga, he tries to avoid fighting Ranmaru if necessary.

If Nobunaga escapes his grasp, Mitsuhide will need to retreat to rebuild his forces. Taking Azuchi Castle away by force, the castle's original master soon surrounds the castle grounds. Repelling their invasion, Mitsuhide deems himself to be the only one who can end Nobunaga and therefore pursues the retreating Oda forces at Yamazaki. If Ranmaru has survived their previous encounters, Mitsuhide has the option to convince the youth to believe in him. Otherwise, Mitsuhide strikes Nobunaga down yet spares him due to hearing his pupil's pleas to stop. Claiming Nobunaga's power as his own, he laments that he must do so for the lives lost in his campaign.

In the event that Mitsuhide kills Nobunaga at the temple, he swears to create a new land for the people. Ranmaru, spared by his mentor's mercy, angrily vows vengeance for Nobunaga's death. Shortly after,Hideyoshi and the other Oda remnants confronts him. To build the new world he wants, he regrettably slays even the peasants that rise in Nobunaga's name. Eradicating the main armies against him, Mitsuhide nearly becomes ruler of the land. At this moment, Ranmaru suddenly rises in Mino and steals Gifu Castle -the place that started it all- away from him. Wanting to explain himself to his pupil, Mitsuhide hurries inside the castle to try to reason with the youth. The young man can't forgive Mitsuhide's utter betrayal and commences a duel that ends his life. Although a sadden Mitsuhide prepares to join him, he realizes his act would cheat the lives he took. Dropping his sword, he realizes what it means to truly believe in others.

Samurai Warriors 2 has Mitsuhide as a rōnin looking to serve a worthy lord who will end the land's wars. After he witnesses Nobunaga's resounding victory at Okehazama, Mitsuhide joins his ranks as a loyal officer and helps the retreat at Kanegasaki. Even so, he often finds himself doubting his lord's methods and tries to vie for an alternative solution. He offers Nagamasa a chance to formerly plead for surrender at Odani Castle but Nagamasa instead commits suicide in front of his brother-in-law. After the battle of Saika village, Mitsuhide realizes that he participated in a massacre and finds himself questioning his desires.

Deciding that he would be the one to end the chaos, he leads a revolt at Honnōji and duels Nobunaga in the burning compound. However, he finds himself unable to deal the decisive blow and tearfully states that he still wishes to see the land Nobunaga would create. Seeing their guard down, Magoichi snipes Nobunaga and Mitsuhide is blamed for his lord's death. Bearing the burden of the false claim, he makes a stand at Yamazaki, defeats Hideyoshi's troops, and avenges his lord's death by killing Magoichi. After this battle, Mitsuhide becomes the shogun of Japan and the land is peaceful.

In his dream mode, he deals with the Anti-Mitsuhide coalition led by Ieyasu at Anegawa right after the Battle of Yamazaki. His forces include the Date troops, the remaining Uesugi troops, and the Sanada clan. Kotarō also ambushes Mitushide in his goal for chaos.

Samurai Warriors: Katana introduces Mitsuhide in the Ascendancy scenario's second chapter. During the Oda's retreat from Kanegasaki, he teaches the protagonist how to use a bow in order to take out the enemy's well-placed archers. His betrayal at Honnōji is later enacted, though the player's arrival prevents him from killing Nobunaga. Despite the support of his men, he is bested in combat and dies. Mitsuhide's coup succeeds in the Savior scenario, but this time the Saika Renegades are his enemy as they interfere with his pursuit of Nō. He hunts them relentlessly before giving in to exhaustion. His death by the protagonist's hands leaves the Akechi army in shambles.

Like his previous story, Mitsuhide begins his career as a wandering rōnin in the third title. He finds himself within the Oda troops, building up in ranks to eventually become a trusted family vassal. Armed with his knowledge of rifles, he helps prepare the formations for Nagashino with the earnest desire to see Nobunaga's vision for the land. Upon learning this, his lord retorts that he isn't needed for such a goal as he merely wants to move the times with his military measures. Instead of assuring him, Nobunaga dares Mitsuhide to bet on whether the land will be peaceful under his control. Thinking that the land is in Nobunaga's palm after their victory, the eastern parts of the land submit and the Oda continue westward to suppress the Saika Renegadesand the Mōri. Learning that the enemy is led under the supposedly dead Motonari, Mitsuhide calls upon the aid of his friend, Motochika, for naval support. Once Motochika sails in with his navy from Shikoku, the Oda army has the manpower they need to counter the Mōri fleet at Kizugawaguchi. As a portion of the Saika renegades flail for a surrender, Mitsuhide escorts them towards the Oda forces. Nobunaga notices them yet won't allow mercy. After Kazumasu carries out their swift execution, Mitsuhide is stunned by his master's relentless cruelty yet asserts his belief in Nobunaga.

Even so, his heart wavers after they suppress the Saika renegades and continue to fight the Mōri. His lord eventually begins plans to conquer Shikoku as if to taunt Mitsuhide's torn loyalties. Confessing his confusions to Motochika, his friend remarks that he should just do what he believes is just. Ultimately deciding to protect Motochika and the peaceful land he desires, he regretfully leads an army against Nobunaga at Honnōji. While distraught for causing Nobunaga's death, Motochika encourages him to take full responsibility as they face Hideyoshi's army at Yamazaki. Coordinating with his friend, they take out the enemy front line and utilize Motochika's navy to sneak to the front of Hideyoshi's main camp. While Motochika proceeds to deal with the northern Toyotomi troops, he is caught in a trap set by Kanbei. Although Mitsuhide rescues him and wins the battle, the wound Motochika suffers costs him his life.

Shocked by the loss, Mitushide renounces his name in grief and hides from the world in secrecy in nod to his fictional survival from Yamazaki. His disappearance allows Hideyoshi to continue his conquest of the land before he departs from the world. Many years later, Ieyasu calls for his aid against the Western Army. While reminiscing about his past with his guest, Mitsuhide decides to stand once more in battle to repay the debt of the lives lost for the land of peace. Ieyasu accepts his pleas for forgiveness and Mitsuhide joins the Eastern Army at Sekigahara as a mysterious helper. Content to see the land united, Mitushide lays down his arms and stays with Ieyasu. Playing Motochika's shamisen, he wonders what his friend would say about him. Ieyasu complements his meager tune, stating that the instrument must be happy to be with him -an answer that Mitsuhide modestly accepts.

The protagonist in Samurai Warriors Chronicles can aid Mitsuhide and the Saitō at Inabayama Castle. Despite their efforts, the Oda prevail and absorbs them into their forces. Mitsuhide's general activities remains the same as his main series' counterpart, betraying Nobunaga and perishing at Yamazaki. In Gracia's Gaiden stage, Mitsuhide appears as the main antagonist since he is trying to have his daughter submit to her arranged marriage. Although he is defeated by his daughter, Mitsuhide gets his way.

Sengoku Musou 3: Empires includes Mitsuhide in three different stories. Nobunaga's own story route has him escort Yoshiaki Ashikaga to safety while keeping the shogun's pettiness in check. In Motochika's story, he returns from his voyage to see Gracia only to find her missing, leading him to abscond his post in search for her. Mitsuhide's disappearance drives much of the scenario's plot until rumors of his alleged betrayal at Honnōji begin to circulate. He and his daughter reunite in Yamazaki, though the Oda retainers continue to hound them in spite of his innocence. To protect his family, he accepts his role as a scapegoat and leaves the country by ship. His defeat at Yamazaki is reprised in Hideyoshi's story, though the latter allows him to live and repent by joining the Hashiba forces. Pained by the stigma of being a traitor, he is consoled by Nene who encourages him to create a peaceful world with her husband as a way of atoning.

In Samurai Warriors 4, he first appears in the Oda story with Hisahide to see Nobunaga in action at the battle of Okehazama. While Hisahide gloats about himself and calls himself the greatest villain of the era, Mitsuhide questions whether Nobunaga is truly the man to unite the land. After Okehazama, Mitsuhide is impressed and joins Nobunaga for his conquest of the capital and worries about Hisahide's loyalty and sanity. He performs his duties and keeps an eye on Hisahide at Asan, Kanegasaki, Noda-Fukushima, and Nagashino. While Nobunaga returns to the capital, Mitsuhide assists Motochika to aid his unification of Shikoku. After they captureKoshōshō, Mitsuhide resumes his duties in the mainland.

He returns to aid the conquest of Kii Province, shocked and depressed that Hisahide betrayed the Oda. He wants to reconcile his differences with his friend but ultimately fails. Realizes that Hisahide wanted to reclaim his fate and finally taking Hisahide's words to heart, he feels Nobunaga has become unjust and resolves to raise troops at Honnōji. While he claims to wish to liberate the land from Nobunaga's villainy, his convictions waver when he corners him. Mitsuhide regretfully kills him at Nobunaga's insistence. In the Legend of Land Untied, he resolves to take responsibility for his deed and meets his end at Yamazaki.

The 4-II Rebellion Story has him continue to befriend and question Hisahide's loyalties to Nobunaga. In spite of Hisahide's repeated inclinations to betray Nobunaga, Mitsuhide remains loyal to his lord throughout the entire scenario. Scorned, Hisahide goes through the effort to have Mitsuhide falsely accused of betrayal during his rebellion at Honnōji. Mitsuhide arrives too late to clear the misunderstanding. He and his daughter perish while trying to defend Nobunaga from Hisahide.